Left ventricular remodelling in masters athletes

Abstract Funding Acknowledgements Type of funding sources: Other. Main source(s): I have received a research fellowship grant from the UK based charity Cardiac Risk in Young Objectives We investigated effect long-term exercise and sex on left ventricular (LV) geometry large group female male masters athletes. Background Studies assessing LV athletes are scarce. Methods Different types were identified according to echocardiography-derived relative wall thickness (RWT) mass (LVM) values as per international guidelines. 4 groups formed: normal (normal LVM/normal RWT), concentric hypertrophy (increased LVM/increased eccentric remodeling RWT). Results A total 277 healthy, elite, caucasian endurance (65% female; mean age54.8 ± 7.7 years) assessed. The exercising for 32 11.7 years completed median 70 competitions including 13 marathon-type competitions. Females exhibited lower absolute LVM (127.7 30.31g vs 196.57 45.0g, p < 0.001), indexed (76.8 18.0 g/m2 vs. 103.6 22.7 g/m2; RWT (0.36 0.07 0.42 0.08; 0.001) end-diastolic dimension (LVEDD) (46.3 4.1 mm 50.1 5.11 mm, but greater LVEDD (27.7 2.7mm/m2 26.5 2.7 mm/m2, compared with Most showed (72% 38% athletes, P significantly less (12% 35%, (5% 13%, = 0.01) (table & figure). Conclusions sex-specific response chronic is observed. Male exhibit more frequently abnormal and/or hypertrophy. Cohort characteristics N 97 Female 180 value Age (years) 55.0 9.0 54.7 6.9 0.68 Years 32.0 12.8 33.3 11.1 0.14 Mass (g) 127.7 30.31 45.0 <0.001 Indexed (g/m2) 76.8 (mm) 46.3 (mm/m2) 27.7 Normal Remodeling 36 (37) 130 (72) Eccentric Hypertrophy 14 (14) 18 (10) 0.27 Concentric 34 (35) 23 (13) 9 (5) 0.01 Left Ventricular, LVEDD: Ventricular End Diastolic Dimension Figure. Patterns